The research investigated the adaptation of Karen youths in Chiang Mai municipality under its socio-economic contexts. The focus was on cultural adaptation, relationships of male and female youths, their new group formation in the urban environment, and attitudes toward their lifestyles from the perspectives of rural and urban youths. The youths were divided into four groups: students, youths in religious organizations, youths in non-governmental organizations, and working youths. The investigation revealed that their adaptation strategies included changing their names, accumulating economic and educational capital, assimilating with the mainstream culture by means of dress, beauty rhetoric, language use, consumption, and creation of male-female relationships. The space was based on formal and informal institutions, which were a part of youth culture and urban society. The connection of oneself and his/her hometown society was done to establish acceptance and emphasize his/her membership in the family and hometown society, leading to the creation of individual, social and life meanings in the future.